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Nicola Maffulli Selected Research

Hyaluronic Acid (Hyaluronan)

9/2023Investigation into the effect of epidermal growth factor and hyaluronic acid on fracture healing in a rat femoral fracture model.
12/2021Management of facet joints osteoarthritis associated with chronic low back pain: A systematic review.
11/2021The Impact of Hyaluronic Acid on Tendon Physiology and Its Clinical Application in Tendinopathies.
5/2021Safety and efficacy of umbilical cord-derived Wharton's jelly compared to hyaluronic acid and saline for knee osteoarthritis: study protocol for a randomized, controlled, single-blind, multi-center trial.
8/2020Current pharmacological approaches to the treatment of tendinopathy.
2/2020Umbilical cord-derived Wharton's jelly for regenerative medicine applications.
9/2017Extracorporeal shockwaves therapy versus hyaluronic acid injection for the treatment of painful non-calcific rotator cuff tendinopathies: preliminary results.
4/2017Hyaluronic acid increases tendon derived cell viability and proliferation in vitro: comparative study of two different hyaluronic acid preparations by molecular weight.
7/2016Viscosupplementation with intra-articular hyaluronic acid for hip disorders. A systematic review and meta-analysis.
4/2014Six-months pain relief and functional recovery after intra-articular injections with hyaluronic acid (mw 500-730 KDa) in trapeziometacarpal osteoarthritis.
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Nicola Maffulli Research Topics

Disease

75Tendinopathy (Tendonitis)
01/2023 - 04/2002
68Pain (Aches)
04/2024 - 01/2002
40Wounds and Injuries (Trauma)
05/2024 - 01/2007
35Osteoarthritis
01/2024 - 04/2007
28Rupture
02/2024 - 06/2005
27Rotator Cuff Injuries
11/2023 - 08/2007
15Infections
04/2024 - 03/2008
15Knee Osteoarthritis
12/2023 - 04/2007
11Inflammation (Inflammations)
12/2021 - 10/2010
10Stress Fractures (Stress Fracture)
04/2023 - 05/2010
8Low Back Pain (Lumbago)
04/2024 - 01/2021
8Congenital Abnormalities (Deformity)
11/2020 - 05/2005
6COVID-19
02/2024 - 07/2020
6Necrosis
02/2024 - 12/2010
6Hallux Valgus
09/2023 - 10/2009
5Hypersensitivity (Allergy)
04/2024 - 10/2007
5Osteoporosis
09/2023 - 06/2012
5Osteonecrosis (Kienbock's Disease)
04/2023 - 04/2012
5Neoplasm Metastasis (Metastasis)
01/2021 - 05/2008
5Tendon Injuries
01/2020 - 01/2007
5Arthritis (Polyarthritis)
04/2018 - 01/2009
4Bursitis (Adhesive Capsulitis)
12/2023 - 03/2015
4Heterotopic Ossification (Ectopic Ossification)
11/2023 - 01/2021
4Fibromyalgia (Fibrositis)
07/2023 - 08/2021
4Postmenopausal Osteoporosis
08/2021 - 03/2015
4Cicatrix (Scar)
12/2017 - 03/2008
3Contracture
07/2023 - 01/2016
3Anterior Cruciate Ligament Injuries
06/2023 - 01/2010
3Compartment Syndromes
06/2023 - 07/2012
3Postoperative Pain
06/2023 - 10/2009
3Femoracetabular Impingement
01/2023 - 01/2018
3Hypertrophy
12/2022 - 09/2022
3Joint Diseases (Joint Disease)
03/2022 - 12/2005
3Athletic Injuries (Sports Injuries)
12/2021 - 01/2021
3Hip Osteoarthritis (Coxarthrosis)
10/2020 - 01/2009
3Chronic Exertional Compartment Syndrome
01/2019 - 07/2012
3Shock
09/2017 - 10/2009
3Wound Infection (Wound Infections)
01/2014 - 03/2008
2Ankle Injuries (Ankle Injury)
05/2024 - 06/2013
2Femoral Fractures (Femoral Fracture)
09/2023 - 08/2021
2Bone Fractures (Bone Fracture)
07/2023 - 01/2003
2Dry Eye Syndromes (Dry Eye Syndrome)
06/2023 - 11/2022
2Hernia (Hernias)
06/2023 - 04/2023
2Patellar Dislocation
05/2023 - 01/2016

Drug/Important Bio-Agent (IBA)

15CollagenIBA
09/2023 - 11/2007
14Adrenal Cortex Hormones (Corticosteroids)IBA
02/2024 - 12/2005
12Hyaluronic Acid (Hyaluronan)IBA
09/2023 - 03/2012
11Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2021 - 01/2012
10CytokinesIBA
09/2023 - 01/2013
6Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
11/2023 - 04/2014
5Analgesics (Analgesic Drugs)IBA
11/2023 - 05/2008
5Biomarkers (Surrogate Marker)IBA
01/2023 - 04/2016
5mesoglycanIBA
12/2022 - 01/2018
5Metalloproteases (Metalloproteinases)IBA
01/2015 - 06/2005
4Anti-Bacterial Agents (Antibiotics)IBA
12/2023 - 04/2013
4MicroRNAs (MicroRNA)IBA
01/2023 - 01/2019
4EnzymesIBA
01/2013 - 04/2007
4Matrix Metalloproteinases (MMPs)IBA
01/2013 - 06/2005
3Diphosphonates (Bisphosphonates)IBA
12/2023 - 03/2015
3Collagen Type I (Type I Collagen)IBA
01/2020 - 07/2008
3TenascinIBA
01/2015 - 06/2008
3Aprotinin (Trasylol)FDA Link
08/2013 - 10/2007
3SolutionsIBA
01/2012 - 09/2005
2Duloxetine Hydrochloride (Cymbalta)FDA Link
07/2023 - 01/2021

Therapy/Procedure

54Therapeutics
11/2023 - 01/2007
38Conservative Treatment
04/2024 - 01/2002
24Injections
09/2023 - 10/2007
20Arthroplasty
12/2023 - 01/2005
20Osteotomy
12/2021 - 05/2005
16Extracorporeal Shockwave Therapy
01/2023 - 01/2007
12Knee Replacement Arthroplasty (Total Knee Replacement)
12/2023 - 04/2007
12Debridement
01/2023 - 02/2007
11Sutures (Suture)
05/2024 - 03/2008
11Tendon Transfer
02/2024 - 11/2007
11Hip Replacement Arthroplasty (Total Hip Replacement)
11/2023 - 02/2008
10Reoperation
12/2023 - 12/2011
8Arthrodesis
09/2023 - 01/2005
8Intra-Articular Injections
05/2023 - 01/2012
8Operative Surgical Procedures
10/2022 - 08/2009
7Tenotomy
12/2021 - 04/2002
6Activities of Daily Living (ADL)
01/2024 - 11/2009
6Fasciotomy
06/2023 - 01/2015
6Aftercare (After-Treatment)
04/2023 - 06/2009
6Minimally Invasive Surgical Procedures
11/2022 - 10/2009
6Length of Stay
06/2022 - 10/2009
5Meniscectomy
12/2023 - 01/2011
5Drug Therapy (Chemotherapy)
09/2023 - 01/2012
5Suture Anchors
01/2022 - 01/2004
5Prolotherapy
10/2021 - 01/2017
4Resistance Training
04/2023 - 01/2007
4Decompression
01/2021 - 01/2013
4Radiotherapy
01/2021 - 05/2008
3Ultrasonic Therapy
08/2023 - 04/2012
3Denervation
01/2022 - 04/2012
3Tenodesis
12/2011 - 03/2008
3Diathermy
06/2011 - 01/2007
2Biological Therapy
09/2023 - 01/2013
2Physical Therapy Modalities (Physical Therapy Technique)
09/2023 - 08/2006
2Surgical Amputation (Amputations)
07/2023 - 07/2019
2Transplantation
04/2023 - 09/2021